General Information about the Course

Course Code:	DNT 121
Course Title:	Committee 4: Biological Organization
Course Semester:	2. Semester / Spring
Course Credits:	Theoretical Practical Credit ECTS 6 3 8 7
Language of instruction:	EN
Prerequisite of the course:	No
Ders İş Deneyimini Gerektiriyor mu?:	No
Type of course:	Necessary
Level of course:	Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Course Lecturer(s):	Asst. Prof. Sercan Doğukan Yıldız (Anatomy) / Prof. Ahmet Kaya Emek (Biochemistry) / Asst. Prof. Ezgi Gizem Berkay (Medical Biology) / Prof. Dr. Tangül Müdok (Histology and Embryology) / Asst. Prof. Hasan Hüseyin Şahin (Physiology)
Course Assistants:

Purpose and content of the course

Course Objectives:	To understand the transition to histological tissue organization within biological organization after biological regulation, classification of tissues and macro anatomy. To comprehend the laws of movement of biophysics within the organization related to movement. To know the chemistry of macromolecules that make up tissues. To understand physiology related to tissue stimulation.
Course Objective:	To know intracellular traffic and signals. To comprehend the organization formed by cytoskeleton and adhesion molecules. To identify histological and chemical elements of tissues. To get information about physiology. To associate it with the laws of physics. To understand the effects of mutagens, characteristics of cell aging. To understand molecular controls in the cell cycle.
Mode of Delivery:	Face to face

Learning Outcomes

Knowledge (Described as Theoritical and/or Factual Knowledge.)

1) Students know the signal mechanisms in the cell.

2) Knows the types of microscopes

3) Students know the molecules of intercellular interconnection.

4) Distinguish healthy tissues according to their histological features and classify specialized tissues.

5) Students know histological tissue organization, and macroanatomy related to movement.

6) Students comprehend the effects of physiological stimulation and its relations with the laws of physics.

7) Students know bioelectrical potentials.

8) Students know the working mechanisms of the hematopoietic system.

Skills (Describe as Cognitive and/or Practical Skills.)

1) Students can list bones of the skull and limb joints and bones.

2) Students know basic histological tissues.

Competences (Described as "Ability of the learner to apply knowledge and skills autonomously with responsibility", "Learning to learn"," Communication and social" and "Field specific" competences.)

1) Students demonstrate responsibility and self-discipline.

2) Students are productive and questioning.

3) Students speak their mother tongue effectively, strive to speak a foreign language.

4) Students can work independently and take responsibility.

Course Topics

Week	Subject
Related Preparation	Pekiştirme
1)	BIOCHEMISTRY: Carbohydrates and their biological importance MEDICAL BIOLOGY: Cell signal transduction 1: signal transduction and short-term cellular responses HISTOLOGY-EMBRILOGY: Connective Tissue 1
2)	BIOCHEMISTRY: Glycosaminoglycan s-Proteoglycans MEDICAL BIOLOGY: Cell signal transduction-2 :signaling pathways that control gene activity HISTOLOGY-EMBRILOGY: Connective Tissue 2
3)	BIOCHEMISTRY: Amino acids and proteins MEDICAL BIOLOGY: Adhesion molecules HISTOLOGY-EMBRILOGY: Epithelial Tissue
4)	ANATOMY: Bones of the Skull and Vertebral Column BIOCHEMISTRY: Biochemistry of Connective Tissue MEDICAL BIOLOGY: Cytoskeletal proteins HISTOLOGY-EMBRIOLOGY: Glandular Epithelium
5)	ANATOMY: Bones of the upper limb BIOCHEMISTRY: Bone Biochemistry MEDICAL BIOLOGY: Intracellular Protein Traffic, Protein Destruction (Proteasome Chaperone) HISTOLOGY-EMBRIOLOGY: Cartilage Tissue
6)	ANATOMY: Joints of the upper limb MEDICAL BIOLOGY: Mutagenic effects HISTOLOGY-EMBRIOLOGY: Bone Tissue
7)	ANATOMY: Bones of the lower limb MEDICAL BIOLOGY: Cell aging: apoptosis, necrosis mechanism HISTOLOGY-EMBRIOLOGY: Hematopoiesis PHYSIOLOGY: Hematopoietic Sys.
8)	ANATOMY: Joints of the lower limb HISTOLOGY-EMBRIOLOGY: Nerve Tissue PHYSIOLOGY: Excitable Tissues and Action Potential
9)	ANATOMY: Muscles of the lower limb MEDICAL BIOLOGY: Cell Cycle - Cell Division - Meiosis- Mitosis HISTOLOGY-EMBRIOLOGY: * Muscle Tissue * Cardiac Muscle PHYSIOLOGY: Muscle Physiology BIOPHYSICS: Laws of Motio
10)	MEDICAL BIOLOGY: Cell Cycle - Checkpoints- Cyclins HISTOLOGY-EMBRIOLOGY: Gametogenesis
References: Anatomy: **Arifoğlu, Y. (2021). Her Yönüyle ANATOMİ 3. BASKI. **FH, N. (2010). İnsan Anatomisi Atlası (6. Baskı). Cumhur M.(Edt), Nobel Tıp Kitabevi, İstanbul. Biochemistry: **Wictor W. Rodwell, D. A. B., Kathleen M. Botham, Peter J. Kennelly, P. Anthony Weil. (2019). Harper'ın Resimli Biyokimyası (31 ed.). Güneş Tıp Kitabevi. **Gürdöl, F. (2021). Tıbbi Biyokimya (5 ed.). Nobel Tıp Kitapevi. Medical Biology: **Klug, W. S., Cummings, M. R., Spencer, C. A., & Öner, C. (2011). Genetik kavramlar. Palme Yayıncılık. **Nalini Chandar, S. V. (2012). Lippincott's Hücre ve Moleküler Biyoloji. Nobel Tıp Kitapevi. **Geçkil, H., Özmen, M., & Yeşilada, Ö. (2011). Moleküler Hücre Biyolojisi. Palmae yayıncılık. Histology-Embriology: **Junqueira, L. C. U., Carneiro, J., Aytekin, Y., & Solakoğlu, S. (2009). Temel histoloji: text & atlas. Nobel Tıp Kitabevleri. **Mescher, A. (2015). Junqueira's Temel Histoloji Atlas Kitap. İstanbul: Nobel Tıp Kitabevleri Tic. Ltd. Şti. **Demir, R. (2006). Histoloji ve Hücre Biyolojisi: Patolojiye Giriş. Palme Yayıncılık. **Ross, M., & Pavlina, W. (2014). Histoloji Konu Anlatımı ve Atlas (6. Baskı). B. Baykal (Çev.), Ankara: Palme Yayıncılık. **Yüncü, P. D. M. (2016). Genel Histoloji ve Genel Embriyoloj. Çukurova Nobel Tıp Kitapevi. **Can, A. (2018). Yaşam Bilimlerinde A’dan Z’ye Mikroskopi. Ankara Nobel Tıp Kitapevi. Physiology: **Hall, J. (2016). Guyton ve Hall tıbbi fizyoloji (13. Baskı). Ankara: Güneş Tıp Kitabevleri. **Widmaier, E. P., Raff, H., & Strang, K. T. (2014). Vander insan fizyolojisi: vücut fonksiyon mekanizmaları. Güneş Tıp Kitabevleri. Biophysics: **Jewett, J. W., & Serway, R. (2008). Physics for scientists and engineers with modern physics. Vectors, 1, 2.

Ders - Program Öğrenme Kazanım İlişkisi

No Effect	1 Lowest	2 Average	3 Highest

Ders Öğrenme Kazanımları	1	1	2	2	3	4	5	6	7	8	9	10	11	12
Program Outcomes
1) The normal, abnormal and pathological structures and functions related to oral and dental health in detail.
2) The basic and up-to-date knowledge required by the dentistry profession.
3) The integration of knowledge from different disciplines in the clinic phase and to put their knowledge into practice.
4) Applying knowledge in a holistic approach in professional practice.
5) Evaluating the accuracy, reliability and validity of the knowledge.
6) Showing a systematic approach to diagnosis.
7) Delivering optimum care for patients with correct diagnosis and treatment plan.
8) Conduct a clinical study or a project individually in the field of dentistry.
9) Take responsibility for the use of all technological tools used in dental treatment.
10) Take responsibility in planning and management of either routine applications or complex and unforeseen problems.
11) Participate in national and international academic studies by adopting lifelong learning, share and compare written, verbal and visual information with their colleagues.
12) Follow the evidence-based dentistry knowledge and use the up-to-date knowledge in professional practice within the framework of national values and country facts for the benefit of the society.
13) Use the information and communication technologies at the level required by the field of dentistry.
14) Take part and responsibilities in preventive programs at the social level, and ensure the protection and development of health by applying modern treatment methods with an approach that is patient-oriented, in line with human rights and compatible with the health economy.
15) Organize and implement social responsibility projects and activities.
16) Have proficiency in one foreign language at minimum B1 Level according to European Language Portfolio Global Scale, have written and oral communication skills and follow the developments in their field.
17) Apply the principle of entrepreneurship, business practices and processes with innovative technology in dentistry.
18) Are aware of the significance of ethical rules and legal responsibilities required by the profession.
19) Have knowledge about teamwork, leadership, risk management, patient safety, universality of social rights, social justice, quality management, personal development, environmental protection, occupational health and safety in the delivery and management of oral and dental healthcare services.
20) Implement the required practices in the clinic management, auxiliary personnel training, prevention methods from occupational diseases.

Course Teaching, Learning Methods

Q & A
Case Problem Solving/ Drama- Role/ Case Management
Laboratory
Quantitative Problem Solving
Fieldwork
Group Study / Assignment
Individual Assignment
WEB-based Learning
Internship
Practice in Field
Project Preparation
Report Writing
Seminar
Supervision
Social Activity
Occupational Activity
Occupational Trip
Application (Modelling, Design, Model, Simulation, Experiment et.)
Reading
Thesis Preparation
Field Study
Student Club and Council Activities
Other
Logbook
Interview and Oral Conversation
Research
Watching a movie
Bibliography preparation
Oral, inscribed and visual knowledge production
Taking photographs
Sketching
Mapping and marking
Reading maps
Copying textures
Creating a library of materials
Presentation

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance		% 0
Laboratory		% 0
Application		% 0
Practice Exam		% 0
Quizzes		% 0
Homework Assignments		% 0
Presentation		% 0
Project		% 0
Special Course Internship (Work Placement)		% 0
Field Study		% 0
Article Critical		% 0
Article Writing		% 0
Module Group Study		% 0
Brainstorming		% 0
Role Playing + Dramatizing		% 0
Out of Class Study		% 0
Preliminary Work, Reinforcement		% 0
Application Repetition etc.		% 0
Homework (reading, writing, watching movies, etc.)		% 0
Project Preparation + Presentation		% 0
Report Preparation + Presentation		% 0
Presentation / Seminar Preparation + Presenting		% 0
Oral examination		% 0
Midterms	1	% 40
Final	1	% 60
Report Submission		% 0
Bütünleme		% 0
Kanaat Notu		% 0
Committee		% 0
Yazma Ödev Dosyası		% 0
Portfolio		% 0
Take-Home Exam		% 0
Logbook		% 0
Discussion		% 0
Participation		% 0
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

Calculation of Workload and ECTS Credits

Activities	Number of Activities	Workload
Course Hours	10	90
Laboratory	10	30
Application
Practice Exam
Special Course Internship (Work Placement)
Field Work
Study Hours Out of Class
Article Critical
Article Writing
Module Group Study
Brainstorming
Role Playing + Dramatizing
Out-of-Class Study (Pre-study, Reinforcement, Practice Review, etc.)	10	40
Homework (reading, writing, watching movies, etc.)
Project Preparation + Presentation
Report Preparation + Presentation
Presentation / Seminar Preparation + Presenting
Oral examination
Preparing for Midterm Exams	7	14
MIDTERM EXAM (Visa)	1	1
Preparing for the General Exam	14	56
GENERAL EXAM (Final)	1	1
Participation
Discussion
Portfolio
Take-Home Exam
Logbook
Total Workload		232
ECTS (30 saat = 1 AKTS )		7